Hi, Welcome to JA and thanks for this question. . It is the antonym for homogeneous, meaning a structure with similar components. Hyperechoic. Telomere shortening was observed with increasing PDs. Of the 353 patients with T1c, 66% of the patients were in the Gleason group of 2-6, 27% had a Gleason score of 7, and 7% had a . A heterogeneous mass is tissue in the body that's more dense or solid than usual. For example, a dermoid cyst has heterogeneous attenuation on CT. Cancer Is Heterogeneous Jean Marc Guinebretiere. The nodules were subdivided into the following groups by size: 1 to 1.9, 2 to 2.9, 3 to 3.9, and ≥4 cm and the percent of nodules in each group was 49%, 27%, 14%, and 11% . It is the antonym for homogeneous, meaning a structure with similar components. Differences in colour, shape, and size can make a tissue look heterogeneous. That includes Mister Hand. Results: The median age was 69 years, and the median follow-up of surviving patients was 47 months. Breast tissue is composed of milk glands, milk ducts and supportive tissue (dense breast tissue), and fatty tissue (nondense breast tissue). Heterogenous refers to a structure having a foreign origin. Does heterogeneous mass mean cancer? I sincerely ***** ***** I have helped you and that I have earned my 5-star rating today! Cancer is a heterogeneous disease. Homogeneous is good. It occurs in 40% of women and while normal, can make it more difficult to detect breast cancer on mammography. They may be associated with malignancy, but they are also present in benign conditions, as fibroadenoma, in areas of fibrosis or trauma. Heterogeneous is a word pathologists use to describe tissue that looks very different from one area of the tissue to the next. However, if a mass is discovered on the pancreas, there's an 85 percent chance that it will be the deadly adenocarcinoma. However, heterogeneity in cancer is not limited to differences between different patients, but also occurs within a single patient (Figure 1). best wishes. I recently went for a follow up mammogram and they found : Heterogenous calcifications seen in the posterior region of left breast 5 o'clock Heterogenous calcifications seen in the posterior central region of right breast Heterogenous calcifications seen in the posterior region of right breat 11 o'clock Im having biopsy on 4/4/11 would anyone have any helful information It is the antonym for homogeneous, meaning a structure with similar components. For example, a dermoid cyst has heterogeneous attenuation on CT. It is the antonym for homogeneous, meaning a structure with similar components. There is mild insertional patellar tendinosis and slight adjacent soft tissue edema. The uterus is the hollow, pear-shaped pelvic organ where fetal development occurs. NCI's Dictionary of Cancer Terms provides easy-to-understand definitions for words and phrases related to cancer and medicine. Some tumors are paucicellular, such as infiltrating lobular carcinoma in its . Helpful - 1. sadafi. Another common reason is a condition called endimitrosis which is a benign cyst/growths or tumors You could call the doctor and ask. Ask U.S. doctors your own question and get educational, text answers — it's anonymous and free! It is not normal, but it is not prostate cancer either. type (ie, core needle biopsy, surgical biopsy, and so on); (2) tumor size (increasingly small, owing to routine breast cancer screening); and (3) the proportion of viable tumor cells present within the sample. 2. in genetics, said of a trait that can be produced by different genes or combinations of genes. I'm sorry to hear about your symptoms. Question: I have an ultrasound scan report that says I have a thickening of the endometrium 11mm and the myometrium appears heterogeneous with a focal hypoechoic area of fibroid tissue seen within the lower right lateral uterine wall measuring 1.3cm The uterus appears anteverted and of normal size and shape. menstrual cycle abnormalities, such as heavy bleeding and . However, heterogeneity in cancer is not limited to differences between different patients, but also occurs within a single patient (Figure 1). Or it may spread throughout the body. This intrapatient or intratumoral heterogeneity can present great challenges for cancer treatment. Heterogeneous can be used to describe the way the tissue looks with or without a microscope. They are usually in a group and are smaller in size than dystrophic calcifications. Prosititus can show higher PSA, so can having sex prior to the test. Painful ejaculation. 1 doctor answer • 1 doctor weighed in. Heterogeneous refers to a structure with dissimilar components or elements, appearing irregular or variegated. Cancer is a heterogeneous disease. Some tumors are paucicellular, such as infiltrating lobular carcinoma in its . One may also ask, does heterogeneous mass mean cancer? Be cool, be calm. Dr. Treatment if needed, is very good. Other types of cancer can form in the uterus . heterogeneous just means that the texture of your uterus is not uniform. Understanding tumor heterogeneity may be the next big quest in cancer science, as differences between cells within a tumor can have important consequences for how cancers are diagnosed and treated. A heterogeneous liver would be the exact opposite and is remarkable for lumps and bumps of varying size which, dependin. Hyperechoic . This intrapatient or intratumoral heterogeneity can present great challenges for cancer treatment. Does heterogeneous mean cancer? Those excluded usually had a high cystic component. Pancreas: Please go online and look up "Heterogeneous pancreas". Answer: The normal liver is homogeneous, by which I mean, it is firm, red-brown and has the same consistency throughout by gross (macroscopic) examination. PCa is slow growing, even in advanced cases like mine it is slow growing. Hi There. Endometrial cancer begins in the layer of cells that form the lining (endometrium) of the uterus. So bone pain, especially in the back, can be a symptom of advanced prostate cancer. However, heterogeneity in cancer is not limited to differences between different patients, but also occurs within a single patient (Figure 1). Heterogenous refers to a structure having a foreign origin. Heterogeneous refers to a structure with dissimilar components or elements, appearing irregular or variegated. 1. consisting of or composed of dissimilar elements or ingredients; not having a uniform quality throughout. These cells are termed cancer stem cells (CSCs), and are marked by the ability to both self-renew and differentiate into non-tumourigenic progeny.The CSC model posits that the heterogeneity observed between tumour cells is the result . It urgently needs new therapeutic strategies to improve the prognosis of TNBC. For example, heterogenous bone . Your PSA is normal though. This intrapatient or intratumoral heterogeneity can present great challenges for cancer treatment. Endometrial cancer is a type of cancer that begins in the uterus. View answer. Cancer is a heterogeneous disease. Heterogeneous renal mass. Endometrial cancer is a type of cancer that begins in the uterus. Based on my experience, Ultrasound is not enough to determine whether a renal mass is cancerous or not, though i read somewhere that there is this Ultra-sound protocol that could differentiate malignancy vs benignity by considering some specific (quite technical) guidelines. Heterogeneous lungs can be caused by varying regional aeration, varying regional perfusion, and ground glass opacities (GGO) representing airspace or interstitial pathology. Perhaps someone else knows. Results: The median age was 69 years, and the median follow-up of surviving patients was 47 months. best wishes. This term means "lots of echoes." These areas bounce back many sound waves. Cancer Risk. "Masses can be tumors [benign or malignant] or non . Hence one needs to convey this to the patients. Depending on the size, heterogeneous masses need to be removed and examined for malignancy. Answered by : Dr. Robert Galamaga ( Hematologist) Read More . Some heterogeneous masses on the ovaries resolve on their own. "If a patient presents with jaundice [yellowing of the skin] and a mass, there is a about a 90 percent chance" that the mass will be malignant, adds Dr. Winter. Please remember to rate my service by selecting the 5-stars at the top of the screen (rating me now does not close your question). But some liver lesions form as a result of cancer. Heterogenous refers to a structure having a foreign origin. Heterogenous refers to a structure having a foreign origin. As a percentage of all patients with prostate cancer, stage T1c continually increased from 6% in 1989 to 47% in 1999. that can be because of fibroids. Quadriceps tendon is normal. Heterogeneously dense breasts is a term used in mammography to describe breasts with a higher percentage of glandular and supportive tissue than fat. BI-RADS classifies breast density into four categories, as follows: (A) Almost entirely fatty breast tissue, found in about 10% of women. Heterogeneous masses are called solid tumors and can be cancerous. Does heterogeneous mass mean cancer? Cancer is a heterogeneous disease. x. . 13.4K views View upvotes View 1 share what does report mean. Helpful - 1. sadafi. It tends to spread to the bones. A Verified Doctor answered. Endometrial cancer begins in the layer of cells that form the lining (endometrium) of the uterus. If the diagnosis is endometrial heterogeneous, it means that there is an inflammatory process in the body. That can be because of fibrosis/Fibroid tumors or Uterine fibrosis. x. . A hypoechoic lesion is an abnormal area that can be seen during an ultrasound examination because it is darker than the surrounding tissue. It does not per se lead to cancer, but the underlying pathology such as Vit D3 deficiency and environmental toxins can increase the risk. Practically from the moment pathologists first looked at human cancers under the microscope, they saw that differing histologic appearances could define distinct subtypes of cancers from the same primary site of origin. Heterogeneous refers to a structure with dissimilar components or elements, appearing irregular or variegated. Noncancerous, or benign, liver lesions are common. Your doctor may call them a mass or a tumor. A total of 9339 nodules ≥1 cm were identified, and 7348 (78%) were evaluated by FNA. For example, a dermoid cyst has heterogeneous attenuation on CT. It does not serve the referring clinicians or the patients well if the radiology report simply mentions the heterogeneity of the lungs without due analysis of the cause of . Although they are of intermediate risk for breast cancer (most commonly, DCIS), they are also associated with benign entities, such as hyalinized/degenerating fibroadenoma, areas of fibrosis, papilloma . For example, a dermoid cyst has heterogeneous attenuation on CT. As a result of this heterogeneity, the bulk tumour might include a diverse collection of cells harbouring distinct molecular signatures with differential levels of sensitivity to treatment. type (ie, core needle biopsy, surgical biopsy, and so on); (2) tumor size (increasingly small, owing to routine breast cancer screening); and (3) the proportion of viable tumor cells present within the sample. However, heterogeneity in cancer is not limited to differences between different patients, but also occurs within a single patient (Figure 1). Cancer is a heterogeneous disease. Solid masses of dense tissue are hypoechoic. Heterogenicity of thyroids indicates non-specific inflammation of the gland as seen in autoimmune thyroiditis. mri knee i have dull ache pain i also have nf1 worried if it could be a sarcoma. Liver lesions are groups of abnormal cells in your liver. There are many articles but most, if not all, report that pancreatic cancer is very uncommon in "heterogeneous pancreas". An enlarged uterus may cause a number of symptoms, such as weakness, cramping, constipation, pain during sex, and menstrual abnormalities. Be patient. A heterogeneous hypervascular thyroid nodule could mean a few different things. No obvious adnexal cyst or mass is demonstrated. When viewed on a mammogram, women with dense breasts have more dense tissue than fatty tissue. Underlying heterogeneous echogenicity might make it difficult to differentiate between benign and malignant nodules on US. Heterogeneous echogenicity of the thyroid gland has been associated with diffuse thyroid disease and benign and malignant nodules can coexist with diffuse thyroid disease. Of the 353 patients with T1c, 66% of the patients were in the Gleason group of 2-6, 27% had a Gleason score of 7, and 7% had a . Doctors who review mammograms are called radiologists. A related discussion, heterogenous uterus and myometrium was started. What does it mean if something is heterogeneous? Hi jupaul, You asked whether "degenerative disc disease at L5-S1" is normal. Breathe in and then breathe out. Annekathryn Goodman, M.D. Every person's cancer develops and grows in its own way and is unique in terms of what therapies it's sensitive to. Prostate cancer can spread to the lymph nodes of the pelvis. What does a hypoechoic lesion in the liver mean? The most common pattern of vascularity in thyroid malignancy is marked intrinsic hypervascularity, which is defined as flow in the central part of the tumor that is greater than that in the surrounding thyroid parenchyma (, Fig 11,).This occurs in 69%-74% of all thyroid malignancies (, 2,, 18).What does it mean when thyroid gland is heterogeneous? Heterogeneous is just a descriptive term and does not mean cancer. Definition of heterogeneous Thus, the aim of this study was to evaluate the influence of underlying thyroid echogenicity on . I'm not sure what "heterogeneous marrow signal intensity" means; it may be normal. The cancer stem cell model asserts that within a population of tumour cells, there is only a small subset of cells that are tumourigenic (able to form tumours). To catch breast cancer early, it's widely recommended that all women, regardless of their breast density, do monthly self-exams, get examined by a doctor annually, and have a . That finding is worth discussion with a doctor specializing in bones. A single group of coarse heterogeneous calcifications has a positive predictive value of slightly less than 15% and it should be placed in BI-RADS assessment category 4B (PPV range >10% to = 50%). Endometrial cancer is sometimes called uterine cancer. As a percentage of all patients with prostate cancer, stage T1c continually increased from 6% in 1989 to 47% in 1999. Endometrial cancer is sometimes called uterine cancer. Does heterogeneous signal intensity mean cancer? It's a normal and common finding. It would need to have a biopsy . What does Hypervascular thyroid mean? heterogeneous just means that the texture of your uterus is not uniform. (B) Scattered areas of dense glandular tissue and fibrous connective tissue ( scattered fibroglandular breast tissue) found in about 40% of women. Specifically, early and mid PDs demonstrated mean telomere length measurements of 10.55 kb and 9.32 kb, respectively. The uterus is the hollow, pear-shaped pelvic organ where fetal development occurs. Triple-negative breast cancer (TNBC) is a highly heterogeneous subtype of breast cancer, showing aggressive clinical behaviors and poor outcomes. Coarse heterogeneous calcifications are irregular calcifications that are between 0.5 mm and 1 mm in size. Other types of cancer can form in the uterus . another common reason is a condition called adenomyosis which is benign glands within the muscle wall. The opposite of heterogeneous is homogeneous. Heterogeneous tumors are divided into spatial and temporal types depending on whether the non-uniform distribution of cancer cells is dispersed across and within disease sites, or if there is cell . A related discussion, heterogenous uterus and myometrium was started. Furthermore, does heterogeneous mean cancer? Dr. Barry T. Kahn from HealthTap explains that heterogeneous masses can be malignant or benign. The late timepoint (PD 60) corresponded with the approximate onset of cellular senescence (Kaul et al., 2012), and had a mean telomere length of 4.52 kb. cancer (it is quite difficult to diagnose uterine cancer, especially in the early stages, since cancerous growth is very similar to myoma). what does heterogeneous appearance of the bone marrow , probably reflects normal variation or red marrow hyperlasia mean on a mri and it says marrow signal is somewhat heterogeneous correction with hematoligc studies. heterogeneous. that can be because of fibroids. This demonstrates . The mean nodule size was 2.6 cm. Nagging pain in the back, hips, or pelvis. Hi There. Heterogeneous refers to a structure with dissimilar components or elements, appearing irregular or variegated. They appear as light gray on the ultrasound. For example, heterogenous bone . Heterogeneous tumors are divided into spatial and temporal types depending on whether the non-uniform distribution of cancer cells is dispersed across and within disease sites, or if there is cell . Cancer Is Heterogeneous Jean Marc Guinebretiere. Dense breast tissue refers to the appearance of breast tissue on a mammogram. Actually heterogenous is a medical term which refers to an uneven or irregular appearance of an organ, Basically, a heterogeneous appearance in terms of the prostate would indicate that the surface of the prostate is irregular and uneven which can occur in many conditions. Bioinformatics analyses have been widely used to identify potential biomarkers for facilitating TNBC diagnosis and . 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